Let’s Discuss Typhoid Vaccines. 

There are 2 routes for Typhoid Vaccines–injection or oral. 

The injection is an inactivated (killed) vaccine. One dose is recommended at least 2 weeks before travel. Repeated doses are recommended every 2 years for people who remain at risk. 

The oral capsule is a live, attenuated (weakened) vaccine. One capsule is taken every other day, for a total of 4 capsules over 8 days. The last dose should be taken at least 1 week before travel. Each capsule should be swallowed whole (not chewed) about an hour before meals with cold or lukewarm water. A booster vaccine is needed every 5 years for people who remain at risk. Important: live typhoid vaccine capsules must be stored in a refrigerator (not frozen). 

Typhoid vaccines are recommended for: 

Travelers to parts of the world where Typhoid is common (but you should still be careful about what you eat and drink.) 

People in close contact with a typhoid carrier. 

Laboratory workers who work with Salmonella typhi bacteria. Typhoid vaccines may be given at the same time as other vaccines. Typhoid vaccines usually do require a prescription. 

Contraindications to Typhoid Vaccine 

Intramuscular injection: 

-Patients with hypersensitivity or anaphylaxis to any component of the vaccine or its container. 

Oral:

-Patients with hypersensitivity to any component of the vaccine or the enteric-coated capsule. 

-Patients with an acute gastrointestinal condition 

-Immunocompromised patients